At Babel, man, in his proud arrogance, decided to grab his future for himself according to his own rules. Consider this, when man puts his future in his own hands it is called humanism, a term we are familiar with today, which teaches that man is all and man is good.
By default humanism is in opposition to God [Rom 1:25; Jam 4:4-6]. Who, then, does this leave as God? Man. It is a religion based upon the presupposition of the non-existence of the supernatural.
Humanism denies the existence of the One it is seeking to usurp as though He is already dead. What this truly means is that the foundation of Humanism is the very real existence of God! Secular origins science fits into this category, which is why it can never arrive at any kind of truth about origins. Humanism stems from the Genesis 3:5 lie. It is the root of it all and no matter what label Man attaches to his Godless beliefs, it all starts at the same place, back in the Garden.
(excerpt taken from Declaring the End from the Beginning – an examination of the events at Babel and how they relate to Bible Prophecy)